Friend murine leukaemia virus
- Friend murine leukaemia virus
-
Murine
leukaemia virus isolated by Charlotte Friend in 1956 whilst attempting to transmit the Erlich
ascites tumour by cell-free extracts. Causes an unusual erythroblastosis-like leukaemia, in which
anaemia is accompanied by large numbers of nucleated red cells in blood. Does not carry
a host-derived oncogene, but seems to induce tumours by proviral insertion into specific regions of host genome.
Dictionary of molecular biology.
2004.
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